Biomotif develop new front end instrumentation for mass spectrometry. The multifunctional proprietary HX-IA Instrument™ has been developed for advanced PROTEOMICS & INTERACTOMICSstudies. This technology is based on several new inventions such as ElectroCapture, Memrane assisted H/DX, Compound Fishing-Epitope Imprinting and on-line pI separation of proteins and peptides.
The HX-IA Instrument™ will provide a better understanding of biomarker targets and there structure/conformation, dynamics and molecular interactions with potential drug candidates in the liquid phase.
Biomotif offer a contract analysis service in the following areas:
HDX Studies-Mode-of-Action (MoA) analysis
- Protein-antibody epitope mapping identification
- Protein-protein or protein-peptide interface mapping
- Bioequivalence studies
- Patent submission/protection information
- H/DX screening for structure based drug design
- Identification of disordered regions in protein constructs that prevent crystallization
- Identifying the effect of mutations on protein stability
- Complementary data to x-ray and NMR data
Scientific Collaboration Partners
We will work with world class scientific partners for technology and method development. Our partners will get access to unique technology for solving complicated analytical tasks as well as copublish with us in high end scientific journals.
The substance library is based upon the active site of the protease inhibitor Cystatin C
More than 25 years of intensive research on the human protein Cystatin C, including identification of its biological active site has lead to production of a large number of small (
ZULA have potent Antibiotic and Antiviral drug candidates based on the elucidation of the structure of the active site of a human protein, Cystatin C.
The mechanism is different compared to all currently available antibiotics, since bacterial strains resistant against all presently available antibiotics still are killed.
Some of our substances show antiviral capability to inhibit the replication of both DNA virus e.g. Herpes simplex and RNA virus e.g. Polio.
We are seeking financial partners for the development and testing of these drug candidates.
ZULA provides high throughput proteomics analyses of clinical samples, first of all blood plasma.
With a special formulation containing exclusive Swedish and Nordic natural ingredients together with Arginine derivative A20, we plan to market our product as a “Swedish Magic Cream”.
P. O. Box 156, SE-182 12 Danderyd
Tel.: +46 70 563 89 53